3-Hydroxy-1,2,3,4-Tetrahydrobenzo[H]Quinoline

3-Hydroxy-1,2,3,4-Tetrahydrobenzo[H]Quinoline - Names and Identifiers

Name	1,2,3,4-tetrahydrobenzo[h]quinolin-3-ol
Synonyms	1H,2H,3H,4H-benzo[h]quinolin-3-ol 1,2,3,4-tetrahydrobenzo[h]quinolin-3-ol 1,2,3,4-Tetrahydrobenzo(h)quinolin-3-ol 1,2,3,4-Tetrahydrobenzo[h]quinolin-3-ol Benzo[h]quinolin-3-ol, 1,2,3,4-tetrahydro- (3S)-1,2,3,4-tetrahydrobenzo[h]quinolin-3-ol (3R)-1,2,3,4-tetrahydrobenzo[h]quinolin-3-ol 3-Hydroxy-1,2,3,4-tetrahydrobenzo[h]quinoline 3-HYDROXY-1,2,3,4-TETRAHYDROBENZO[H]QUINOLINE 3-Hydroxy-1,2,3,4-Tetrahydrobenzo[H]Quinoline 3-Hydroxy1,2,3,4 tetrahydrobenzo H quinolin3ol 3-Hydroxy-1,2,3,4-tetrahydrobenzo[h]quinoline 5423-67-6
CAS	5423-67-6
EINECS	226-556-6
InChI	InChI=1/C13H13NO/c15-11-7-10-6-5-9-3-1-2-4-12(9)13(10)14-8-11/h1-6,11,14-15H,7-8H2/t11-/m1/s1

3-Hydroxy-1,2,3,4-Tetrahydrobenzo[H]Quinoline - Physico-chemical Properties

Molecular Formula	C13H13NO
Molar Mass	199.25
Density	1.219±0.06 g/cm3(Predicted)
Melting Point	148-150 °C
Boling Point	424.3±34.0 °C(Predicted)
Flash Point	210.5°C
Vapor Presure	5.87E-08mmHg at 25°C
pKa	14.33±0.20(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Refractive Index	1.672

3-Hydroxy-1,2,3,4-Tetrahydrobenzo[H]Quinoline - Risk and Safety

Safety Description	24/25 - Avoid contact with skin and eyes.
HS Code	29334900

3-Hydroxy-1,2,3,4-Tetrahydrobenzo[H]Quinoline - Introduction

1,2,3,4-tetrahydrobenzo[h]quinolin-3-ol is an organic compound with a chemical formula of C11H11NO and a molecular weight of 173.21g/mol. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 1,2,3,4-tetrahydrobenzo[h]quinolin-3-ol as a white crystalline solid.
-Melting point: approximately 216-219°C.
-Solubility: It can be dissolved in chloroform, ethanol and ether.

Use:
-Drug research: 1,2,3,4-tetrahydrobenzo[h]quinolin-3-ol is widely used as an intermediate in the synthesis of other biologically active compounds, especially in the field of drug research. It has anti-inflammatory, anti-tumor, anti-virus and anti-bacterial activities, and can be used to develop new drugs.

Preparation Method:
1,2,3,4-tetrahydrobenzo[h]quinolin-3-ol can be synthesized by a variety of methods, one of which is commonly used by hydrogenation reduction reaction:
-First, 1,2,3,4-tetrahydrobenzo [h] quinoline is generated by reaction;
-Then, in the presence of an appropriate catalyst, hydrogen and a catalyst are used for hydrogenation to obtain 1,2,3,4-tetrahydrobenzo[h]quinolin-3-ol.

Safety Information:
- 1,2,3,4-tetrahydrobenzo[h]quinolin-3-ol may cause irritation to the eyes, skin and respiratory tract and direct contact should be avoided.
-When using or handling 1,2,3,4-tetrahydrobenzo[h]quinolin-3-ol, take appropriate personal protective measures, such as wearing gloves, glasses and respiratory protective equipment.
-Avoid contact with oxidants and strong acids during storage and handling to prevent dangerous reactions.
-When symptoms of discomfort after inhalation or contact with 1,2,3,4-tetrahydrobenzo[h]quinolin-3-ol occur, you should seek medical attention immediately.

Please note that the above information is for reference only. If you need specific experimental operations or more detailed information, it is recommended to consult a chemical professional or refer to relevant literature.

Last Update：2024-04-09 21:01:54